2024

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Direct Electron Transfer–Type Oxidoreductases for Biomedical Applications

Keisei Sowa, Junko Okuda-Shimazaki, Eole Fukawa, Koji SODE

Annual Reviews of Biomedical Engineering

In press

 

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Rapid and Convenient Single-chain Variable Fragments-Employed Electrochemical Detection System for C-Reactive Protein Applicable to Point-of-care Testing

Daimei Miura, Saki Motohashi, Ayaka Goto, Hayato Kimura, Wakako Tsugawa, Koji SODE, Kazunori Ikebukuro, Ryutaro Asano

International Journal of Molecular Science

25(5), 2859

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Development of a glycated albumin sensor employing dual aptamer-based extended gate field effect transistors

Mika Hatada, Spyridon Pavlidis, Koji SODE

Biosensors and Bioelectronics

251, 116118

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Development of direct electron transfer type extended gate field effect transistor enzyme sensors for metabolite detection

David Probst, Jack Twiddy, Mika Hatada, Spyridon Pavlidis, Michael Daniele, Koji SODE

Analytical Chemistry

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Development of the BioBattery: a novel enzyme fuel cell using a multicopper oxidase as an anodic enzyme

Kartheek Batchu, David Probst, Takenori Satomura, Koji SODE

Biosensors and Bioelectronics

252, 116092

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Development of an electrochemical impedance spectroscopy immunosensor for insulin monitoring employing pyrroloquinoline quinone as an ingestible redox probe

Mukund Khanwalker, Mika Hatada, Jeffery T. LaBelle, Koji SODE

Biosensors and Bioelectronics

250, 116049

 

 

Exploration and Application of DNA-Binding Proteins to Make a Versatile DNA−Protein Covalent-Linking Patch (D-Pclip): The Case of a Biosensing Element

Erika Komiya, Shouhei Takamatsu, Daimei Miura, Kaori Tsukakoshi, Wakako Tsugawa, Koji SODE, Kazunori Ikebukuro, and Ryutaro Asano

Journal of the American Chemical Society

146, 6, 4087–4097

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2023

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In vivo continuous monitoring of peptides and proteins: Challenges and opportunities

Ellie Wilson, David Probst, Koji Sode

Applied Physics Review

10(4), 041309

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Development of interdigitated electrode based enzyme sensor for triglyceride monitoring using engineered oxygen insensitive glycerol 3-phosphate oxidase

Inyoung Lee, Sheng Tong, Mika Hatada, Adrianna Masterson, Kentaro Hiraka, Junko Okuda-Shimazaki, Wakako Tsugawa, Gary Hughes, Koji SODE

Sensors and Actuators Reports

5,  100164

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Development of an Anti-Idiotype Aptamer-Based Electrochemical Sensor for a Humanized Therapeutic Antibody Monitoring

Madoka Nagata, Jinhee Lee, Taro Saito, Kazunori Ikebukuro, Koji SODE

International Journal of Molecular Sciences

24(6), 5277

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Development of a versatile method to construct direct electron transfer-type enzyme complexes employing SpyCatcher/SpyTag system

Takumi Yanase, Junko Okuda-Shimazaki, Ryutaro Asano, Kazunori Ikebukuro, Koji SODE, Wakako Tsugawa

International Journal of Molecular Sciences

24(3), 1837

 

Surface area independent response of closed bipolar electrodes

David Probst, Inyoung Lee, Jeffrey E. Dick, Koji SODE

Sensors and Actuators Reports

5:100138

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2022

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Microgravity environment grown crystal structure information based engineering of direct electron transfer type glucose dehydrogenase

Junko Okuda-Shimazaki, Hiromi Yoshida, Inyoung Lee, Katsuhiro Kojima, Nanoha Suzuki, Wakako Tsugawa, Mitsugu Yamada, Koji Inaka, Hiroaki Tanaka, Koji SODE

Communications Biology

5:1334

 

Structure of lactate oxidase from Enterococcus hirae revealed new aspects of active site loop function: product inhibition mechanism and oxygen gatekeeper

Kentaro Hiraka, Hiromi Yoshida, Wakako Tsugawa, Ryutaro Asano, Jeffrey T. La Belle, Kazunori Ikebukuro, Koji Sode

 Protein Science

31:10, e4434

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The development of micro–sized enzyme sensor based on direct electron transfer type open circuit potential sensing principle

David Probst, Inyoung Lee, Koji SODE

Electrochimica Acta

426:10, 140798

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A Thiol-Reactive Phenazine Ethosulfate (trPES) – A Novel Redox Mediator for Quasi-Direct Electron Transfer Type Sensors

Maya Fitriana, Kentaro Hiraka, Kazunori Ikebukuro, Koji SODE, Wakako Tsugawa

Sensors and Materials Sensors and Materials

34:6, 2105-2124

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In vitro continuous 3 months operation of direct electron transfer type open circuit potential based glucose sensor: heralding the next CGM sensor

nyoung Lee, Wakako Tsugawa, Kazunori Ikebukuro, Koji SODE

Journal of Diabetes Science and Technology

16(5):1107-1113

 

Development of an electrochemical impedance spectroscopy based biosensor for detection of ubiquitin C-Terminal hydrolase L1

 Jinhee Lee, Bryant Kane, Mukunc Khanwalker, Koji SODE

Biosensors and Bioelectronics

208:114232

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A Glycemia Risk Index (GRI) of Hypo- and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings

David Klonoff et al. (multiple authors including Koji SODE)

 Journal of Diabetes Science and Technology

doi: 10.1177/19322968221085273

 

An Amine-Reactive Phenazine Ethosulfate (arPES) - A Novel Redox Probe for Electrochemical Aptamer based Sensor

Jinhee Lee, Madoka Nagata, Stephen Henley, Kazunori Ikebukuro, Koji SODE

Sensors (MDPI)

24;22(5):1760

 

Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection

Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Koichi Abe, Jinhee Lee, Kinuko Ueno, Ryutaro Asano, Brian V. Jones, Tomohiro Yamada, Tatsuki Nakano, Jiaxing Tong, Asami Hishiki, Kodai Hara, Hiroshi Hashimoto, Koji SODE

Biosensors and Bioelectronics

203:114027

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Light‑induced production of isobutanol and 3‑methyl‑1‑butanol by metabolically engineered cyanobacteria

 Shunichi Kobayashi, Shota Atsumi, Kazunori Ikebukuro, Koji SODE, Ryutaro Asano

Microbial Cell Factories

21:7

 

Transient potentiometry based D-serine sensor using engineered D-amino acid oxidase showing quasi-direct electron transfer property

 Shouhei Takamatsu, Inyoung Lee, Jinhee Lee, Ryutaro Asano, Wakako Tsugawa, Kazunori Ikebukuro, Jeffrey E. Dick, Koji SODE

Biosensors and Bioelectronics

200 :113927

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Development of a POCT type insulin sensor employing anti-insulin single chain variable fragment based on faradaic electrochemical impedance spectroscopy under single frequency measurement

Mukund Khanwalker, Rinko Fujita, Jinhee Lee, Ellie Wilson, Kohei Ito, Ryutaro Asano, Kazunori Ikebukuro, Jeffrey LaBelle, Koji SODE

Biosensors and Bioelectronics

200:113901

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In vitro evaluation of miniaturized amperometric enzyme sensor based on the direct electron transfer principle for continuous glucose monitoring

Yutaro Inoue, Yasuhide Kusaka, Kotaro Shinozaki, Inyoung Lee, Koji SODE

Journal of Diabetes Science and Technology

doi.org/10.1177/19322968211070614

 

 

 

2021

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Clinical Study of a High Accuracy Green Design Blood Glucose Monitor Using an Innovative Optical Transmission Absorbance System

Takeyuki Moriuchi, Yuto Otaki, Hiroya Satou, Fumihiko Chai,Yuma Hayashida, Ryokei Aikawa, Takayuki Sugiyama, Koji SODE

Journal of Diabetes Science and Technology

doi.org/10.1177/19322968211060865

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Current and future prospective of biosensing molecules for point-of-care sensors for diabetes biomarker

Mika Hatada, Ellie Wilson, Mukund Khanwalker, David Probst, Junko Okuda-Shimazaki, Koji Sode

Sensors & Actuators: B. Chemical

351,  130914

 

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Continuous electrochemical monitoring of L-glutamine using redox-probe-modified L-glutamine-binding protein based on intermittent pulse amperometry.

Shouhei Takamatsu, Jinhee Lee, Ryutaro Asano, Wakako Tsugawa, Kazunori Ikebukuro,

Sensors and Actuators B:Chemical

346, 130554

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Artificial complementary chromatic acclimation gene expression system in Escherichia coli

Dwi Ariyanti, Kazunori Ikebukuro, Koji SODE

Microb Cell Fact.

20:128

 

Rapid, convenient, and highly sensitive detection of human hemoglobin in serum using a high-affinity bivalent antibody–enzyme complex

Daimei Miura, Hayato Kimura, Wakako Tsugawa, Kazunori Ikebukuro, , Ryutaro Asano,

TALANTA

234, 122638,

 

 

Electrochemical Quantification of Accelerated FADGDH Rates in Aqueous Nanodroplets.

Kathryn J. Vannoy, Inyoung Lee , Jeffrey E. Dick,

Proceedings of the National Academy of Sciences

118(25) e2025726118,

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G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol.

Kaori Tsukakoshi, Yasuko Yamagishi, Mana Kanazashi, Kenta Nakama, Daiki Oshikawa, Nasa Savory, Akimasa Matsugami, Fumiaki Hayashi, Jinhee Lee, Taiki Saito, Koji SODE, Kanjana Khunathai, Hitoshi Kuno, Kazunori Ikebukuro,

Nucleic Acids Res.

49(11), 6069-6081

 

Data on G-quadruplex topology, and binding ability of G-quadruplex forming sequences found in the promoter region of biomarker proteins and those relations to the presence of nuclear localization signal in the proteins. 

Jinhee Lee , Kentaro Teramoto, Tomomi Yokoyama, Kinuko Ueno, Kaori Tsukakoshi, Koji SODE, Kazunori Ikebukuro,

Data in Brief, 

36 ,107828 

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A self-powered glucose sensor based on BioCapacitor principle with micro-sized enzyme anode employing direct electron transfer type FADGDH.

Inyoung Lee, Junko Okuda-Shimazaki, Wakako Tsugawa, Kazunori Ikebukuro and Koji SODE,

Journal of Physics: Energy, 3, (2021)

034009

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A self-powered glucose sensor based on BioCapacitor principle with micro-sized enzyme anode employing direct electron transfer type FADGDH.

Inyoung Lee, Junko Okuda-Shimazaki, Wakako Tsugawa, Kazunori Ikebukuro and Koji SODE

Journal of Physics: Energy

3, 034009

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Continuous glucose monitoring systems - Current status and future perspectives of the flagship technologies in biosensor research -

Inyoung Lee, David Probst, David Klonoff and Koji Sode

Biosensors and Bioelectronics

181:113054

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Development of an Interdigitated Electrode-Based Disposable Enzyme Sensor Strip for Glycated Albumin Measurement.

Mika Hatada, Noya Loew, Junko Okuda-Shimazaki, Mukund Khanwalker, Wakako Tsugawa, Ashok Mulchandani, Koji SODE,

Molecules

26(3), 734

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Development of glycated peptide enzyme sensor based flow injection analysis system for haemoglobin A1c monitoring using quasi-direct electron transfer type engineered fructosyl peptide oxidase.

Mika Hatada, Satomi Saito, Satoshi Yonehara, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro, 

Biosensors and Bioelectronics

177:112984

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Strategic design and improvement of the internal electron transfer of heme b domain-fused glucose dehydrogenase for use in direct electron transfer-type glucose sensors.

Kohei Ito, Junko Okuda-Shimazaki, Katsuhiro Kojima, Kazushige Mori, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro,

Biosensors and Bioelectronics,

176:112911

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Rational design of direct electron transfer type l-lactate dehydrogenase for the development of multiplexed biosensor.

Kentaro Hiraka, Wakako Tsugawa, Ryutaro Asano, Murat A Yokus, Kazunori Ikebukuro, Michael A Daniele

Biosensors and Bioelectronics

176:112933

 

Rapid and homogeneous electrochemical detection by fabricating a high affinity bispecific antibody-enzyme complex using two Catcher/Tag systems.

Hayato Kimura, Daimei Miura, Wakako Tsugawa, Kazunori Ikebukuro, , Ryutaro Asano

Biosensors and Bioelectronics

175:112885

 

 

 

2020

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A Green Light-Regulated T7 RNA Polymerase Gene Expression System for Cyanobacteria.

Chika Shono, Dwi Ariyanti, Koichi Abe, Yuta Sakai, Ippei Sakamoto, Kaori Tsukakoshi, Koji SODE, Kazunori Ikebukuro

Marine Biotechnology

(2020), on line ahead of print

DOI:10.1007/s10126-020-09997-w

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Creation of a novel DET type FAD glucose dehydrogenase harboring Escherichia coli derived cytochrome b562 as an electron transfer domain

TakumiYanase, JunkoOkuda-Shimazaki, Kazushige Mori, KatsuhiroKojima, WakakoTsugawa, Koji SODE,

Biochemical Biophysical Research Communications

(530(1):82-86

DOI:10.1016/j.bbrc.2020.06.132

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Employment of 1-Methoxy-5-Ethyl Phenazinium Ethyl Sulfate as a Stable Electron Mediator in Flavin Oxidoreductases-Based Sensors

Maya Fitriana, Noya Loew, Arief Budi Witarto, Kazunori Ikebukuro, Koji SODE, Wakako Tsugawa

Sensors (Basel)

20(10):2825

DOI:10.3390/s20102825

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Alteration of Electron Acceptor Preferences in the Oxidative Half-Reaction of Flavin-Dependent Oxidases and Dehydrogenases

Kentaro Hiraka, Wakako Tsugawa, Koji SODE

International Journal of Molecular Sciences

21(11):3797

DOI:10.3390/ijms21113797

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Engineered Glucose Oxidase Capable of Quasi-Direct Electron Transfer after a Quick-and-Easy Modification with a Mediator

Nanami Suzuki, Jinhee Lee, Noya Loew, Yuka Takahashi-Inose, Junko Okuda-Shimazaki, Katsuhiro Kojima, Kazushige Mori, Wakako Tsugawa, Koji SODE

International Journal of Molecular Sciences

21(3):1137

DOI:10.3390/ijms21031137

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